Archive for the ‘science’ Category

Nash remembered on advogato.org

Nash with Browders

(L to R).. a friend, John Nash (standing), Alicia Nash, Felix Browder, Eva Browder, in 1950 at Berkeley, California.

梦中情人
我梦中的妻子有你的身子
我梦中的情人有你的气质
你腹中有我的孩子
你的墓碑上刻着我写的字

你的死亡只是一个比喻
我的生存才是真的问题
你用长发把自己吊死
号啕大哭的是腹中的孩子

Lover in a metaphysical dream

A copy of your body, my dream wife
A copy of your temperament, my dream lover
In your womb is my child
On your tomb engraves my writing.

Your death is but a metaphor
My survival is the true questionable.
you hanged yourself with your long hair
unconsolable sobs in thy womb.

Who? Whom? Whose? faulty line ?

Holy ghost called but Nash no longer hears voices. Hence a beautiful mind

was ejected and pronounced dead on the scene. I wonder if it was Abel who

lost his cool at the waiting game or is it that some other Paraclete made a

miscalculation on the timing belt.

Our bodily vessel is but placeholder for all the mysteries and their

passing and going unto God’s work done or left undone since timely departures of

all saints after Christ walking on this earth. So chime in if you still believe in

παράκλητος …  If not,  the sun never shine in Californification…

Acquiescent right to the photocopy was made by surviving member of the late Felix Browder ( 1927 – 12.10. 2016) of Princeton, originally appeared in Sylvia Nasar’s book “A beautiful mind”.

11
May

USPTO informative opinions

   Posted by: sye   in science

Informative Opinions

9
May

IBM Selectric II innovative design

   Posted by: sye   in science

More from Wikipedia
IBM_Selectric_typewriter

I am waiting for mine to be shipped to me ! It weighs 53 lbs …

6
Apr

Fearful Symmetry – Triolet

   Posted by: sye   in science

From Limiao.net:
“Tony Zee(徐一鸿)写过一本《Fearful Symmetry》,其中fearful不是可怕的意思,是可敬畏的意思。我这篇文章的题目也用可畏的对称性,谈的却不是可敬畏的意思。真正的意思后面就会清楚。”

I came up with this triolet to add my two cents on Oxford debate ‘Poetry is beautiful but Science is what matters’ :

Verse and song gave birth to thee
fearful mechanical and scientific device
Love’s but a dance
of verse and song sublime to thee
A whisper, a glance, this little death –
“Shall we twirl down in Elysian Fields ?”
Verse and song gave birth to thee
fearful mechanical and scientific device

More triolets:

O How can I build a music box
Make spirits move at my fingertips.
The Poet and the pendulum, symphonic nightwish
O How can I build a music box
stuffing it of enchanting stream and lyrical color.
feeds to mighty pythons inside this nodebox
O How can I build a music box,
make spirits move at my fingertips?

* Dead leaves upon the stream
* And dead leaves on the air–
* All of my lost hopes seem
* Dead leaves upon the stream;
* I watch them in a dream,
* Going I know not where,
* Dead leaves upon the stream
* And dead leaves on the air.

“To a fat lady seen from the train”, a triolet written by Charles Darwin’s granddaughter, a scientific lady of the modern age.

* O why do you walk through the fields in gloves,
* Missing so much and so much?
* O fat white woman whom nobody loves,
* Why do you walk through the fields in gloves,
* When the grass is soft as the breast of doves
* And shivering sweet to the touch?
* O why do you walk through the fields in gloves,
* Missing so much and so much?

I later find C.K. Chesterton’s reply exemplified his poetic view on scientific advancement.

* Why do you rush through the fields in trains,
* Guessing so much and so much?
* Why do you flash through the flowery meads,
* Fat-head poet that nobody reads;
* And why do you know such a frightful lot
* About people in gloves and such?
* Why do you rush through the fields in trains,
* Guessing so much and so much?

MARC ZIMMER

NEW LONDON

SOMETIMES THE DIFFERENCE between a $10-an-hour job at a car dealership and winning the $1.4-million Nobel Prize can be smaller than one-millionth the breadth of a hair. That was the case for Douglas Prasher , courtesy shuttle operator at Bill Penney’s Toyota, in Huntsville, Ala.

This year, Osamu Shimomura, Martin Chalfie and Roger Tsien won the chemistry Nobel Prize for their discovery and development of the green fluorescent protein (GFP). Both Chalfie and Tsien acknowledged Douglas Prasher’s contribution to their research. “[Prasher’s] work was critical and essential for the work we did in our lab,” Chalfie said. “They could’ve easily given the prize to Douglas and left me out.”

Very few people know Prasher’s story and how close he came to getting the Nobel Prize. It was Prasher’s 1994 GFP talk at Connecticut College that got me interested in this amazing protein, which has since become such an important part of my academic career. It’s been four years since I last spoke to Prasher, and I was stunned to learn that the man who missed the Nobel chemistry prize by 20 DNA base pairs is now driving a courtesy shuttle at a car dealership. This is not a soap opera, but a real-life tale of life’s cruel twists and turns.

While working at Woods Hole Oceanographic Institute in 1987, Prasher wrote a grant in which he proposed to isolate the GFP gene and clone it from a jellyfish. Essentially, Prasher was trying to find the “recipe” for GFP, so that he might copy it and program another organism to make it. The American Cancer Society granted him $220,000 to undertake the project. Prasher’s ultimate goal was to connect the glowing GFP to otherwise invisible proteins, so that scientists might be able to see when and where they are made.

In the late 1980s, molecular biology was still in its infancy, and cloning a new protein was a painstaking and tedious process. Eventually, Prasher found the GFP gene, sequenced it and cloned it in E.coli, but could not express the fluorescent protein in the bacteria. He came to the conclusion that the bacteria could make GFP but didn’t have the machinery to make it glow. Then his grant ran out. He applied for more funding, but it was denied. Prasher gave up.

If Prasher had had a little more time, he might have realized that what was preventing his bacteria from glowing was only a tiny oversight. When Prasher copied the GFP gene, he also copied 20 additional base pairs before the gene, and it was this little bit of DNA — shorter than one-millionth the breadth of a hair — that was responsible for the GFP folding incorrectly in the bacteria and preventing it from emitting its signature green glow.

Both Chalfie and Tsien requested a copy of Prasher’s GFP gene, and he gave it to them. “I could have hung onto the gene,” Prasher told the Huntsville Times. “But when you’re in that environment and losing public funds, you’ve got an obligation to share.”

Chalfie cleaved off the extraneous DNA and managed to make fluorescent GFP in both bacteria and C. elegans. It was the crucial experiment that showed the potential GFP had as a marker protein. And so Douglas Prasher missed the Nobel Prize by less than the skin of his teeth, and ended up working for a car dealership.

Shortly after giving Chalfie and Tsien copies of his GFP gene, Prasher left Woods Hole for a job researching plant pests for the U.S. Department of Agriculture. Then, after a minor heart attack at age 51, Prasher took a position with AZ Technology, a NASA subcontractor in Huntsville, Ala., developing hand-held sensors designed to detect harmful bacteria in spacecraft. Again, Prasher’s project lost its funding, and he spent a year looking for employment in the science sector in Huntsville. But after a year of searching for a position appropriate for a PhD biochemist, Prasher felt a need to productively occupy himself. That’s when he dropped his car off at Bill Penney’s Toyota, saw an advertisement, and became possibly the world’s most over-qualified courtesy van driver. Ironically, the dealership is on University Drive.

Prasher’s story is a sad one, but a happy ending might still be a possibility. Without him, science would not be the same today, and it is my great hope that Douglas Prasher will finally get the recognition that he so richly deserves.

Marc Zimmer ( mzim@conncoll.edu) is Chemistry Department chairman at Connecticut College and author of Glowing Genes: A Revolution in Biotechnology (Prometheus, 2005).

6
Mar

“In our control” by Laura Eldridge

   Posted by: sye   in science

“In our control – the complete guide to contraceptive choices for women” by Laura Eldridge, forward by Jennifer Baumgardner.

A most informative book on taking charge of one’s own reproductive health.

NJ local news – wife arrested for killing husband with Thallium

I look on the bright side, she is still innocent on this Valetine’s Day until proven guilty as charged: “Thallium Poisoning”.

Defense lawyer of the accused is Steven Altman, who represented Dharun Ravi, a Rutgers University freshman who was accused of using a webcam to invade the privacy of his college roommate, Tyler Clementi.

Xiaoye Wang, the husband, 39 years of age, is dead now. Dr. House and his team were too late to save him due to the winter snow condition at Princeton Medical Center after two weeks diagnostics.

What a pity, all for slapping the mother-in-law in the face when she was visiting the wife and taking care of the new born grandson. Now two-year-old Issac is believed to be in a blackhole of the American legal system . Since his parents’ divorce case wasn’t finalized, now father died, mother’s in jail accused of the killing, who will save Issac? Blessed is the child – falling in the Business of Being Born.

LOVE CAN BE REAL, BUT HARD TO BE TRUE; UXORIOUS IS THY NAME

Poll ————–> :
YOU BE THE JUDGE:

1. I acquit the accused
2. I pardon the accused
3. I dare the accused
4. I damn the accused
5. I AM Prussian Blue
6. I AM the accused
7. Who? What? When? Why?
Parliament of Foules

9
Feb

Francisco J. Ayala

   Posted by: sye   in science

From levesque Diary (http://www.kuro5hin.org/story/2008/10/21/17299/771)
Fact: One out of five pregnancies ends in spontaneous miscarriage

“If God explicitly designed the human reproductive system, is God the biggest abortionist of them all?”

-Francisco J. Ayala, Geneticist and Dominican priest

http://www.sciam.com/article.cfm?id=the-christian-mans-evolution

9
Feb

OpenSceneGraph

   Posted by: sye   in science

About Author:
Rui Wang is a sofware engineer at the Chinese Academy of Surveying and Mapping and the manager of osgChina, the largest OSG discussion website in China. He is one of the most actve members of the ofcial OSG community, who contributes to the serializaton I/O, GPU-based partcle functonalites, BVH and animated GIF plugins, and other fixes and improvements to the OSG project. He translated Paul Martz’s OpenSceneGraph Quick Start Guide into Chinese in 2008, and wrote his own Chinese book OpenSceneGraph Design and Implementaton in 2009, cooperatng with Xuelei Qian. He is also a novel writer and a guitar lover.

Xuelei Qian received his B.Sc. degree in Precision Instrument Engineering from Southeast University, Jiangsu, China, and his Ph.D. degree in applied graphic computng from the University of Derby, Derby, UK in 1998 and 2005, respectvely. Upon completon of his Ph.D. degree, he worked as a postdoctoral research fellow in the Dept. of Precision Instrument and Mechanology at Tsinghua University and his current research interests include E-manufacturing, STEP-NC and intelligent CNC, and virtual reality engineering.

A quick overview of rendering middleware:
Before entering the world of OpenSceneGraph, we assume that you are already experienced
in OpenGL programming. You work with stacks of matrices, set pipeline states, look for new
extensions, call rendering APIs or commands and immediately draw them on a context, no
mater if you are enjoying or sufering from the whole process.
A rendering middleware is a soluton that raises the level of abstracton and eases the
complexity of using a low-level OpenGL API, at the cost of fexibility. The concepts of
modularity and object-orientaton are ofen applied to manage graphics primitves,
materials, and diferent visual data sets in user applicatons, saving much development
tme and allowing new functonalites to be combined as modules and plugins.
OpenSceneGraph is a well-designed rendering middleware applicaton. It is actually a
retained rendering (or deferred rendering) system based on the theory of scene graph,
which records rendering commands and data in a bufer, for executng at some other
tme. This allows the system to perform various optmizatons before rendering, as well as
implement a multthreaded strategy for handling complex scenes.

Scene graphs
A scene graph is a general data structure that defnes the spatal and logical relatonship
of a graphical scene for efcient management and rendering of graphics data. It is typically
represented as a hierarchical graph, which contains a collecton of graphics nodes including
a top-level root node, a number of group nodes each of which can have any number of child
nodes, and a set of leaf nodes each of which has zero child nodes and that serve together
as the botom layer of the tree. A typical scene graph does not allow a directed cycle (where
some nodes are connected in a closed chain) or an isolated element (a node that has no
child or parent) inside of itself.
Each group node can have any number of children. Grouping these child nodes allows them
to share the informaton of the parent and be treated as one unit. By default, an operaton
performed by a parent propagates its efects to all of its children.
It also happens that certain nodes have more than one parent node, in which case the
node is considered to be “instanced”, and the scene graph can be defned as a directed
acyclic graph (DAG). Instancing produces many interestng efects, including data sharing
and mult-pass rendering.
The concept of scene graph has been widely applied in many modern sofware and
applicatons, for instance, AutoCAD, Maya, CorelDraw, VRML, Open Inventor, and the
one that we are going to investgate–OpenSceneGraph.

The OpenSceneGraph project was initated as an avocaton by Don Burns in 1998. He used to
work for SGI and is a hang-gliding enthusiast. He wrote a simplifed SGI Performer-like scene
graph API on a humble Linux PC, named SG, which was the prototype of OSG.
In 1999, Robert Osfeld, a design consultant for a hang-glider manufacturer, started to take
part in this young project. He suggested contnuity to develop SG as a standalone, open
source project and soon ported its elements to Windows. At the end of the year, Robert
took over the project and changed its name to OpenSceneGraph. The project was then fully
rewriten to take advantage of C++ standards and design paterns.
In 2001, in response to the growing interest in the project, Robert set up OpenSceneGraph
Professional Services. He gave up the opportunity to work for other companies, and went
full-tme providing both commercial and free OSG services. Don also formed his own
company, Andes Computer Engineering, and contnues to support the development of OSG.
The frst OpenSceneGraph birds-of-a-feather (BOF) meetng occurred the same year, at
SIGGRAPH 2001, with only 12 people atending. Afer that, atendance at the OSG BOF
contnues to grow every year, with more and more people getng to know this great
OpenGL-based API.
The Producer library, which was initally created to provide windowing and mult-pipe
graphic system integratons for customer’s needs, was added, along with other two
important libraries, osgText and osgFX, in 2003. Then, in 2005, OSG 1.0 was announced,
to the delight of over 1,100 members in the mailing list.

8
Oct

雄文共赏

   Posted by: sye   in multimedia, science

*鍾哲明教授 评《零八憲章》

*余杰:且看北大僵尸教授如何批判零八宪章

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